TEL AVIV: US President Joe Biden on Wednesday, after meeting Israeli leaders in Tel Aviv, unveiled a $100 million deal to allow desperately needed humanitarian aid to enter worn-torn Gaza, where one million people have fled their homes amid withering Israeli air strikes.

Meanwhile, he also announced plans for "unprecedented" aid for Israel and the Palestinians in Gaza and the West Bank, as part of a wider $100 billion package that includes support for Ukraine.

Biden plans to give $10 billion aid from the massive aid deal to Israel despite global protests amid anger over Tuesday's attack on Gaza's Al-Ahli Hospital in which 500 Palestinians were martyred.

After face-to-face talks in Israel and intense telephone diplomacy with Egypt, Biden said a limited number of trucks would be allowed to cross the shuttered Rafah crossing from Egypt into Gaza from Friday.

It would be the first international relief to enter Gaza since October 7, when Hamas launched shock raids into Israel, killing 1,400 people, mostly civilians, and seizing about 200 hostages.

Since then, Israel has besieged the Palestinian enclave, launching wave after wave of air strikes, enforcing a blockade and deploying tens of thousands of troops to the border

The United Nations (UN) and humanitarian groups have begged for the military stranglehold on Gaza to be eased, to allow supplies of water, food, fuel and medicines to enter.

Top UN humanitarian official Martin Griffiths on Wednesday said the situation in Gaza was dire, with hospitals overwhelmed, more than 3,000 Gazans were martyred and 12,500 injured.

"The pace of death, of suffering, of destruction," he said "cannot be exaggerated."

Over 100 trucks have been waiting for days on the Egyptian side of the border to enter Gaza, but have not been allowed to enter Gaza as Israel fears aid deliveries could be used as cover to bring weapons or divert them into the hands of Hamas, the governing enclave. Israel has already launched multiple air strikes at the border crossing.

Meanwhile, Egypt controls the border and fears throwing open the gates would bring tens of thousands of refugees to its territory.

After what he described as a "blunt" telephone call with Egyptian President Abdel Fattah al-Sisi, Biden indicated that about 20 trucks would enter Gaza to start with, with more to come if all sides agree.

"We want to get as many of the trucks out as possible," Biden said aboard Air Force One. "If Hamas confiscates it or doesn't let it get through... then it's going to end because we're not going to be sending any humanitarian aid to Hamas."

Israeli officials said the deliveries would be limited to "food, water and medicine", and that the effort was conditional on aid not being used by Hamas.

The UN's Griffiths estimated that about 100 trucks per day were needed to meet the needs in Gaza.

Biden on Wednesday delivered full US backing for Israel in person, on a solidarity visit in which he blamed the Islamic Jihad Group in Gaza for the deadly rocket strike on the hospital and announced the resumption of urgent aid to the besieged Palestinian enclave.

The US president's whistlestop trip came just hours after Tuesday night's attack at the Ahli Arab hospital in the Gaza Strip, sparking fury in Arab countries which blame Israel and protests in Muslim countries from Egypt to Pakistan.

The horror of the hospital deaths overshadowed Biden's high-stakes regional visit, with Jordan cancelling a summit between King Abdullah II, Biden, Palestinian President Mahmud Abbas and Egyptian President Abdel Fattah al-Sisi.

Israel's military campaign to destroy Hamas, which is holding 199 hostages in the besieged territory, has now claimed the lives of 3,478 people, according to health officials, a vast majority including civilians and children.

Arab countries have almost universally blamed Israel for the hospital strike, either directly or through media — including Egypt, Jordan and the UAE, which are among the region's few countries which have diplomatic relations with Israel.

The Organisation of Islamic Cooperation (OIC) —a 57-member bloc of Muslim-majority countries — denounced Israel's backers for granting the country "impunity" in its war with Gaza.

In the besieged enclave, the hospital explosion brought new horrors after 12 days of sustained bombardment that Israel says targets Hamas and which has destroyed entire city blocks.

More than a million people have been displaced ahead of an anticipated Israeli ground offensive, according to the UN.